GHK-CU 100mg

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GHK-Cu is a copper-binding tripeptide composed of glycine, histidine, and lysine, known for its role in skin regeneration and wound healing. It is widely studied for its potential to support collagen production, reduce inflammation, and improve overall skin and hair health.

GHK-Cu (Glycyl-L-Histidyl-L-Lysine-Copper) is a naturally occurring copper-binding peptide first identified in human plasma. It is found in various tissues and fluids, including saliva and urine, and plays a role in wound healing, tissue remodeling, skin regeneration, and anti-inflammatory activity. The peptide has been widely studied for its applications in dermatology, regenerative medicine, and anti-aging research.


Composition:

GHK-Cu is a tripeptide composed of the following amino acids, with a tightly bound copper(II) ion:

  • Glycine (G)

  • Histidine (H)

  • Lysine (K)

  • Copper ion (Cu²⁺)

Benefits:

Scientific and clinical studies (primarily in vitro and animal models, with some human cosmetic applications) have shown that GHK-Cu may provide the following benefits:

  • Promotes Wound Healing:

    • Stimulates angiogenesis (formation of new blood vessels), increases collagen and glycosaminoglycan synthesis, and supports tissue repair.

  • Anti-Inflammatory Properties:

    • Suppresses pro-inflammatory cytokines (e.g., TNF-α, IL-6), contributing to reduced inflammation in injured tissues.

  • Supports Skin Regeneration and Anti-Aging:

    • Enhances skin elasticity, reduces fine lines and wrinkles, and improves skin tone by promoting fibroblast activity and collagen production.

  • Hair Growth Support:

    • May stimulate hair follicle enlargement and prolong the anagen (growth) phase, based on topical use studies.

  • Antioxidant and DNA Repair Support:

    • Protects cells from oxidative stress and has shown potential in upregulating DNA repair genes in aging-related research.

  • Immune Modulation and Tissue Remodeling:

    • Modulates the immune response while promoting removal of damaged tissue components.


Dosage Protocol:

Disclaimer: The following is based on research and common practice in clinical and investigational contexts. GHK-Cu is not FDA-approved for therapeutic use and should be used under appropriate supervision.

Injectable Protocol (Subcutaneous):

  • Dosage:
    1–2 mg per injection

  • Frequency:
    1–2 times per week for general regenerative or anti-aging support
    For wound healing, may be used every 1–2 days in localized administration

  • Route of Administration:
    Subcutaneous injection near the site of injury or systemically (e.g., abdominal fat)

  • Cycle Duration:
    4–6 weeks for therapeutic cycles
    May be followed by a rest period or transitioned to a maintenance phase (e.g., weekly injections)


Summary:
GHK-Cu is a naturally occurring copper peptide with demonstrated roles in tissue repair, anti-inflammation, skin regeneration, and hair support. Composed of glycine, histidine, lysine, and a bound copper ion, its biological activity is supported by decades of research. While widely used in cosmetic and experimental contexts, its therapeutic use remains investigational and should be approached with appropriate care.

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