SS-31 (10mg)

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SS-31 (Elamipretide) is a synthetic tetrapeptide designed to target and protect mitochondria by binding to cardiolipin in the inner mitochondrial membrane. It enhances cellular energy production, reduces oxidative stress, and supports mitochondrial function. Research suggests SS-31 may improve heart, brain, muscle, and kidney health, with potential applications in age-related diseases and fatigue. While still investigational, it shows promise in improving mitochondrial performance and overall cellular resilience.

Composition

  • SS‑31, also known as Elamipretide, is a synthetic tetrapeptide composed of four amino acids: D‑Arg‑dimethylTyr‑Lys‑Phe‑NH₂. It’s specifically designed to target the inner mitochondrial membrane, where it binds to the lipid cardiolipin, helping stabilize mitochondrial structure and reduce oxidative damage.

Benefits

SS‑31 offers a wide range of potential therapeutic effects, all tied to enhancing mitochondrial health and function:

  • Improved mitochondrial energy production
    Enhances ATP generation in tissues with high energy demands—like the heart, brain, and muscles. May boost endurance and reduce fatigue.

  • Cardioprotection & tissue resilience
    Demonstrated benefits include reduced damage from ischemia-reperfusion injury and heart failure models.

  • Neuroprotection & brain health
    May protect against cognitive decline and neurodegenerative conditions (e.g., Alzheimer’s, Parkinson’s, ALS) by safeguarding mitochondrial function.

  • Visual function improvement
    Clinical trials in patients with age-related macular degeneration (AMD) suggest SS‑31 may enhance low-light vision and reading acuity.

  • Kidney support & anti-fibrotic effects
    In various kidney disease models, SS‑31 improved renal function, reduced fibrosis, and protected mitochondrial integrity.

  • Metabolic benefits
    Animal studies show potential improvements in insulin sensitivity and liver health.

  • Anti-aging potential
    In aged mice, SS‑31 increased lifespan, improved muscle strength, and overall healthspan.

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