Semax is not a stimulant but exerts its effects through modulation of neurotrophic and neurotransmitter systems, particularly BDNF and dopaminergic/glutamatergic pathways.
Benefits of Semax:
Semax has been used clinically in Russia for over two decades, particularly for neurological conditions such as stroke recovery, cognitive impairment, and neurodegenerative disorders. Its mechanisms are largely related to neuroprotection, neuromodulation, and anti-inflammatory effects.
Clinically Supported and Research-Backed Benefits:
- Neuroprotection
- Reduces neuronal damage in models of ischemia and oxidative stress
- Used as part of post-stroke therapy in Russia to improve recovery outcomes
- Cognitive Enhancement
- Enhances attention, memory, and learning in both healthy individuals and those with cognitive deficits (especially in stress or fatigue-related cognitive decline)
- Increased BDNF Expression
- Upregulates brain-derived neurotrophic factor, supporting neuroplasticity, synaptic function, and long-term potentiation
- Mood Regulation
- Modulates neurotransmitters such as dopamine and serotonin, contributing to anxiolytic and potential antidepressant effects
- Improved Adaptation to Stress
- May attenuate the negative effects of chronic stress on the brain, possibly via interaction with the HPA axis
- Anti-inflammatory Effects
- Exhibits local and systemic anti-inflammatory properties, potentially aiding in neurological recovery
Sample Dosage Cycle/Protocol:
Semax is typically administered intranasally, which allows for rapid central nervous system delivery without significant systemic effects.
General Cognitive or Nootropic Use:
- Dosage: 300–600 mcg per administration
- Frequency: 1–2 times per day
- Cycle Duration: 5–10 consecutive days, followed by a break (e.g., 1–2 weeks off); repeat as needed
For Neurological Recovery (e.g., Post-Stroke or Cognitive Decline):
- Dosage: 600–1200 mcg per day, divided into 2–3 doses
- Frequency: Daily
- Cycle Duration: 10–14 days (as used in Russian clinical practice)
Administration Notes:
- Intranasal solution is typically administered in microgram doses per nostril, with a maximum of 2–3 sprays per administration.
- Use a clean, sterile nasal applicator and avoid contamination.
- Keep refrigerated if using reconstituted peptide form.
Reviews
There are no reviews yet.