BPC 157 (Body Protection Compound 157) is a synthetic peptide derived from a protein found in human gastric juice. It is primarily studied for its potential to accelerate tissue repair and promote healing in various types of injuries, including those affecting muscles, tendons, ligaments, nerves, and the gastrointestinal tract. BPC 157 has been shown in animal studies to exert protective effects under conditions of physical stress, inflammation, and injury, although clinical data in humans remain limited.
Composition:
BPC 157 is a pentadecapeptide, meaning it consists of 15 amino acids. It is a fragment of the larger body protection compound (BPC) found naturally in human gastric juice.
- Amino Acid Sequence:Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
- Molecular Weight: ~1419 Da
- It is water-soluble and typically prepared for subcutaneous or intramuscular injection, depending on the targeted tissue.
Benefits:
BPC 157 has been investigated mainly in animal models, with some anecdotal support in human use. Proposed benefits, supported by preclinical studies, include:
- Accelerated Soft Tissue Healing:
- Promotes repair of tendons, ligaments, and muscle tissue following injury or overuse.
- May stimulate angiogenesis (formation of new blood vessels) to support blood flow in damaged tissues.
- Gastrointestinal Protection:
- Originally studied for its protective effects on the stomach lining, BPC 157 may help in conditions like gastric ulcers and inflammatory bowel disease (IBD) in experimental models.
- Neuroprotective and Nerve Healing Effects:
- Shown to support nerve regeneration and protect neurons in injury models, though human data are lacking.
- Anti-Inflammatory Properties:
- Reduces markers of systemic and local inflammation in rodent studies.
- Joint and Connective Tissue Support:
- Frequently used in research related to arthritis, tendonitis, and ligament repair.
Dosage Protocol:
Disclaimer: The following dosage protocol is based on common practices observed in research settings and should not be interpreted as medical advice. BPC 157 is not currently approved for therapeutic use in humans.
Typical Research Protocol:
- Dosage:
- 200–500 mcg per injection
- Total daily dose may be split into two injections if needed
- Frequency:
- Once or twice daily depending on the goal and severity of injury
- Route of Administration:
- Subcutaneous (SC): Near the site of injury for localized effects
- Intramuscular (IM): In or near affected muscles/tendons
- Systemic use: Some researchers administer it subcutaneously into the abdominal area for general healing or GI-related goals
- Cycle Duration:
- 2 to 4 weeks is common for soft tissue healing
- Can be extended based on response, with a 2-week break between cycles often recommended
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